Ponatinib API And Intermediates
Ponatinib is an orally bioavailable multitargeted receptor tyrosine kinase (RTK) inhibitor with potential antiangiogenic and antineoplastic activities. Ponatinib inhibits unmutated and all mutated forms of Bcr-Abl, including T315I, the highly drug therapy-resistant missense mutation of Bcr-Abl. This agent also inhibits other tyrosine kinases including those associated with vascular endothelial growth factor receptors (VEGFRs) and fibroblast growth factor receptors (FGFRs); in addition, it inhibits the tyrosine kinase receptor TIE2 and FMS-related tyrosine kinase receptor-3 (Flt3). RTK inhibition by ponatinib may result in the inhibition of cellular proliferation and angiogenesis and may induce cell death. Bcr-Abl is a fusion tyrosine kinase encoded by the Philadelphia chromosome.
Our Ponatinib API and Intermediates is as following,we have all the below API and intermedites offering all year.
Ponatinib API cas 943319-70-8,Ponatinib Cas 694499-24-6,Ponatinib Cas 18087-73-5,Ponatinib Cas 943320-50-1,Ponatinib Cas 943320-61-4,Ponatinib Cas 694499-26-8
China Ponatinib API cas 943319-70-8,Ponatinib Cas 694499-24-6,Ponatinib Cas 18087-73-5,Ponatinib Cas 943320-50-1 Supplier  Shandong Haohong Biotechnology Co., Ltd. , https://www.haohongpharma.com
Brake Part - Truck & Trailer Automatic Slack Adjuster with OEM Standard 79208
Product details:
1-Original No.: 79208
2-body no. 3185, 26T, 145, 14mm bushing
3-High quality low price prompt delivery
4-The automatic slack adjuster is application for MAN.
Part NO
Spline
Body NO
Arm Hole Length
Bushing
Application
79208
26
3185
145
Φ14
MAN
Illustration for the slack adjuster:
company Profile
The high-quality products of Hangzhou LOZO Machinery mainly include: Manual & automatic slack adjusters for European, American, Japanese and South Korean market; Brake s-camshafts and repair kits; Spring brake chambers; Brake shoe assemblies and repair kits; Air brake valves; Quick release valve assemblies; Quick couplings assemblies; High-strength bolts and nuts, holders nylon washer chains, etc, nearly one thousand sorts and more than a dozen of series.
Mainly apply for: BPW, Volvo, YORK, SCANIA, TRAILER, ROR SAF, FREHAUF, MERCEDES, MAN, ZF, DAF, RENAUT, RABA, NEOPLAN, TEC, SMB, RVI, BENDIX, MERITOR, SPICER, EATON, UNIVERSAL, WAGNER, HENDRICKSON, DEXTER, MACK, HINO, Nissan, MITSUBISHI, ISUZU and so on.